L-Serine

Compare every L-Serine product across UK retailers on Suppio, ranked by true value - price per active dose, not pack size. Prices refreshed daily.

Non-essential amino acid involved in phospholipid synthesis and cognitive function

We rank L-Serine by price per gram of active ingredient - not by pack size - so a bigger tub with a worse price per dose can't outrank a smaller one that's actually cheaper.

What it is

L-Serine is a non-essential amino acid, which is a building block for proteins that the body can produce on its own without needing it from food. It plays a key role in creating phospholipids, which are fatty substances that make up the membranes surrounding every cell in the body.

Why it's used

It is primarily used to support cognitive function, which refers to the mental processes we use to learn, remember, and think. Because of its role in cell membrane health, it is often taken to help maintain the structure and function of brain cells.

How it's made

To produce this supplement commercially, manufacturers typically use a process called fermentation. This involves using specific bacteria or fungi in large tanks to break down sugars, which causes the microorganisms to produce the amino acid as a byproduct. The L-Serine is then filtered out, purified, and dried into a powder for capsules or tablets.

What it typically costs

L-Serine is generally mid-range in price. This is because the fermentation process required to produce it at scale is more complex than the simple extraction used for basic vitamins, but there is enough global supply and competition to keep it from becoming a luxury-priced ingredient.

Dosage by purpose

PurposeTypical studied doseEvidence
GRIN2B-related neurodevelopmental disorder500 mg per kilogram of bodyweight per day in 4 doseslimited
reduction of neurotoxic 1-deoxysphingolipids400 mg per kilogram of bodyweight per day for 52 weekslimited
pediatrics400-600 mg per kilogram of bodyweight per daylimited
  1. https://pmc.ncbi.nlm.nih.gov/articles/PMC10452085 (PubMed)
  2. https://pmc.ncbi.nlm.nih.gov/articles/PMC9382310 (PubMed)
  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC11901643 (PubMed)
  4. https://pmc.ncbi.nlm.nih.gov/articles/PMC10746402 (PubMed)

How Suppio ranks

Suppio matches identical products across UK retailers by barcode, then ranks by price per active dose rather than sticker price. Value rankings only ever include listings Suppio has independently verified against the live retailer page - unverified data is shown on each product’s own page but excluded from ranking.

Prices across our retailer network are refreshed at least daily.

FAQ

What is L-Serine?

Non-essential amino acid involved in phospholipid synthesis and cognitive function

How does Suppio calculate the best-value L-Serine?

We rank L-Serine by price per gram of active ingredient - not by pack size - so a bigger tub with a worse price per dose can't outrank a smaller one that's actually cheaper.

Are these prices verified?

Suppio matches identical products across UK retailers by barcode, then ranks by price per active dose rather than sticker price. Value rankings only ever include listings Suppio has independently verified against the live retailer page - unverified data is shown on each product’s own page but excluded from ranking.

How often are L-Serine prices updated?

Prices across our retailer network are refreshed at least daily.

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